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Elevated interleukin-17A levels despite reduced microRNA-326 gene expression in celiac disease patients under gluten-free diet

Introduction: The microRNA-326 (miR-326) gene, by targeting ETS Proto-Oncogene 1 (ETS1), regulates the differentiation and interleukin-17A production of T helper 17 (Th17) cells. Celiac disease (CD) is an intestinal autoimmune disorder, in which the cascade of Th17 cells plays an important role in i...

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Main Authors: Nafari Maedeh, Asri Nastaran, Rostami-Nejad Mohammad, Forouzesh Flora, Ehsani-Ardakani Mohammad Javad, Jahani-Sherafat Somayeh, Rezaei-Tavirani Mostafa, Aghdaei Hamid Asadzadeh
Format: Artigo
Language:Inglês
Published: Sciendo 2022-09-01
Series:Romanian Journal of Internal Medicine
Subjects:
autoimmune diseases
celiac disease
gene expression
micrornas
reverse transcriptase polymerase chain reaction
Online Access:https://doi.org/10.2478/rjim-2022-0011
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