Liquid-Ordered Phase Formation by Mammalian and Yeast Sterols: A Common Feature With Organizational Differences

Here, biophysical properties of membranes enriched in three metabolically related sterols are analyzed both in vitro and in vivo. Unlike cholesterol and ergosterol, the common metabolic precursor zymosterol is unable to induce the formation of a liquid ordered (lo) phase in model lipid membranes and...

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Hlavní autoři:	Alena Khmelinskaia, Joaquim M. T. Marquês, André E. P. Bastos, Catarina A. C. Antunes, Andreia Bento-Oliveira, Silvia Scolari, Gerson M. da S. Lobo, Rui Malhó, Andreas Herrmann, H. Susana Marinho, Rodrigo F. M. de Almeida
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Frontiers Media S.A. 2020-06-01
Edice:	Frontiers in Cell and Developmental Biology
Témata:	ergosterol cholesterol zymosterol fluorescence lifetime imaging microscopy fluorescence spectroscopy plasma membrane
On-line přístup:	https://www.frontiersin.org/article/10.3389/fcell.2020.00337/full
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