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Alpha-Synuclein: Mechanisms of Release and Pathology Progression in Synucleinopathies

The accumulation of misfolded alpha-synuclein (aSyn) throughout the brain, as Lewy pathology, is a phenomenon central to Parkinson’s disease (PD) pathogenesis. The stereotypical distribution and evolution of the pathology during disease is often attributed to the cell-to-cell transmission of aSyn be...

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Détails bibliographiques
Auteurs principaux: Inês C. Brás, Tiago F. Outeiro
Format: Artigo
Langue:Inglês
Publié: MDPI AG 2021-02-01
Collection:Cells
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Accès en ligne:https://www.mdpi.com/2073-4409/10/2/375
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