Nasal Aβ42 mirrors brain amyloid dynamics and cognitive decline across the Alzheimer’s disease continuum

Abstract Early, non-invasive assessment of Alzheimer’s disease (AD) progression remains a key challenge. This study evaluated whether nasal amyloid-β42 (Aβ42) levels reflect brain amyloid dynamics and cognitive decline. Nasal discharge from 161 individuals, ranging from cognitively unimpaired to AD...

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主要な著者:	Da Hae Jung, Gowoon Son, Sheng Min Wang, Seung-Jun Yoo, Ali Jahanshahi, Hyun Kook Lim, Cheil Moon
フォーマット:	Artigo
言語:	Inglês
出版事項:	Nature Portfolio 2025-08-01
シリーズ:	Scientific Reports
主題:	Alzheimer’s disease Amyloid-β 42 Nasal discharge Brain amyloidosis Non-invasive monitoring
オンライン･アクセス:	https://doi.org/10.1038/s41598-025-15230-2
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