EV68-228-N monoclonal antibody treatment halts progression of paralysis in a mouse model of EV-D68 induced acute flaccid myelitis

ABSTRACT In 2014, 2016, and 2018, infection with enterovirus D68 (EV-D68) was associated with outbreaks of a poliomyelitis-like paralytic syndrome, called acute flaccid myelitis (AFM). While only a small fraction of patients infected with EV-D68 developed AFM, this subgroup of patients does not typi...

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Autori principali:	Michael J. Rudy, Courtney J. Wilson, Brendan Hinckley, Danielle C. Baker, Joshua M. Royal, Marshall P. Hoke, Miles B. Brennan, Matthew R. Vogt, Penny Clarke, Kenneth L. Tyler
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	American Society for Microbiology 2025-04-01
Serie:	mBio
Soggetti:	Enterovirus D-68 acute flaccid myelitis treatment monoclonal antibodies
Accesso online:	https://journals.asm.org/doi/10.1128/mbio.03906-24
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