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Unraveling the glycosylated immunopeptidome with HLA-Glyco

Abstract Recent interest in targeted therapies has been sparked by the study of MHC-associated peptides (MAPs) that undergo post-translational modifications (PTMs), particularly glycosylation. In this study, we introduce a fast computational workflow that merges the MSFragger-Glyco search algorithm...

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Autori principali: Georges Bedran, Daniel A. Polasky, Yi Hsiao, Fengchao Yu, Felipe da Veiga Leprevost, Javier A. Alfaro, Marcin Cieslik, Alexey I. Nesvizhskii
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Portfolio 2023-06-01
Serie:Nature Communications
Accesso online:https://doi.org/10.1038/s41467-023-39270-2
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