mEAK-7 Forms an Alternative mTOR Complex with DNA-PKcs in Human Cancer
Summary: MTOR associated protein, eak-7 homolog (mEAK-7), activates mechanistic target of rapamycin (mTOR) signaling in human cells through an alternative mTOR complex to regulate S6K2 and 4E-BP1. However, the role of mEAK-7 in human cancer has not yet been identified. We demonstrate that mEAK-7 and...
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| Автори: | , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Elsevier
2019-07-01
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| Серія: | iScience |
| Онлайн доступ: | http://www.sciencedirect.com/science/article/pii/S2589004219302123 |
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