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Standard versus Pre-emptive Antibiotic Treatment to Reduce the Rate of Infectious Outcomes after Whipple resection (SPARROW): a study protocol for a multicentre, open-label, randomised controlled trial

Abstract Background Consensus and evidence on the impact of pre-emptive antibiotic treatment after pancreatoduodenectomy is lacking, which is reflected by contradictory recommendations in (inter)national guidelines and current clinical practice. Pre-emptive antibiotic treatment may reduce the risk o...

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Hlavní autoři: D. H. M. Droogh, M. G. J. de Boer, J. van Prehn, H. Putter, B. A. Bonsing, K. Bosscha, S. A. W. Bouwense, J. P. B. M. Braak, F. J. H. Hoogwater, D. J. Lips, M. D. P. Luyer, M. W. J. Stommel, J. H. Wijsman, M. G. Besselink, H. C. van Santvoort, B. Groot Koerkamp, A. L. Vahrmeijer, J. S. D. Mieog, for the Dutch Pancreatic Cancer Group
Médium: Artigo
Jazyk:Inglês
Vydáno: BMC 2025-03-01
Edice:Trials
Témata:
Antibiotic prophylaxis
Pre-emptive antibiotic treatment
Extended antibiotic prophylaxis
Antimicrobial policy
Pancreatoduodenectomy
Whipple
On-line přístup:https://doi.org/10.1186/s13063-024-08574-z
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