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Multiplex PCR to Differentiate Monkeypox Virus Clades

We designed a multiplex quantitative PCR to differentiate monkeypox virus clades. For clinical samples collected in the United Kingdom and Nigeria, sensitivity was 78% (95% CI 67.67%–86.14%) and specificity 94% (95% CI 80.84%–99.30%); for samples with cycle thresholds <35, sensitivity was 98% (95%...

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I tiakina i:
Ngā kaituhi matua: Christopher T. Williams, Alessandra Romero-Ramirez, Adeleye Adesola Semiu, Samuel Oluwafunmbi Ifabumuyi, Caitlin Greenland-Bews, Susan Gould, Dominic Wooding, Collette Allen, Anushri Somasundaran, Nicodemus Nnabuike Mkpuma, Dorcas Gado, Jolly Amoche Adole, Abdulakeem Eniola Amoo, Abisola Ajoke Adeyemi, Laure Bosquillon de Jarcy, Christine Goffinet, Jake Dunning, Malcolm G. Semple, Esto Bahizire, Afolabi Akinpelu, Thomas E. Fletcher, Ana I. Cubas-Atienzar, Cristina Leggio, Adeyinka Adedeji, Adesuyi A. Omoare, Thomas Edwards
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Centers for Disease Control and Prevention 2026-02-01
Rangatū:Emerging Infectious Diseases
Ngā marau:
MPXV
monkeypox virus
mpox
viruses
PCR
diagnostics
Urunga tuihono:https://wwwnc.cdc.gov/eid/article/32/2/25-0686_article
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