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12 Altered mechanisms of cell entry in clinical isolates of the seasonal coronavirus OC43

Objectives/Goals: The human coronavirus OC43 is a Betacoronavirus, like SARS-CoV-2, but causes limited disease. Current clinical OC43 strains replicate in airway epithelial cultures while the lab-adapted strains only replicate in immortalized cells. We will identify the host and viral factors causin...

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Главные авторы: Simon Doss-Gollin, Matthew Frieman, Meagan Deming
Формат: Artigo
Язык:Inglês
Опубликовано: Cambridge University Press 2026-04-01
Серии:Journal of Clinical and Translational Science
Online-ссылка:https://www.cambridge.org/core/product/identifier/S2059866126102532/type/journal_article
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