Mitochondrial Genome-Encoded Long Noncoding RNA <i>Cytochrome B</i> (Lnc<i>CytB</i>) and Mitochondrial Ribonucleases in Diabetic Retinopathy

Aim: Hyperglycemia damages mitochondria and downregulates transcription of mtDNA-encoded genes and the long noncoding RNA Lnc<i>CytB</i>, causing mitochondrial genomic instability. The genes encoded by mtDNA are transcribed as large polycistronic transcripts, and the 5′ ends of precursor tRNAs are p...

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Hauptverfasser:	Jay Kumar, Pooja Malaviya, Renu A. Kowluru
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	MDPI AG 2024-07-01
Schriftenreihe:	Biomedicines
Schlagworte:	diabetic retinopathy long noncoding RNA Lnc<i>CytB</i> mitochondria mitochondrial ribonuclease P
Online-Zugang:	https://www.mdpi.com/2227-9059/12/8/1637
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