Colorectal cancer-derived small extracellular vesicles induce TGFβ1-mediated epithelial to mesenchymal transition of hepatocytes

Abstract Background Metastatic disease is the major cause of cancer-related deaths. Increasing evidence shows that primary tumor cells can promote metastasis by preparing the local microenvironment of distant organs, inducing the formation of the so-called “pre-metastatic niche”. In recent years, se...

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Principais autores:	Marzia Pucci, Marta Moschetti, Ornella Urzì, Marco Loria, Alice Conigliaro, Maria Antonietta Di Bella, Rossella Crescitelli, Roger Olofsson Bagge, Alessia Gallo, Mark F. Santos, Caterina Puglisi, Stefano Forte, Aurelio Lorico, Riccardo Alessandro, Simona Fontana
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	BMC 2023-04-01
סדרה:	Cancer Cell International
נושאים:	Colorectal cancer Small extracellular vesicles Transforming growth factor‑β1 (TGFβ1) Hepatocytes Liver metastasis
גישה מקוונת:	https://doi.org/10.1186/s12935-023-02916-8
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