The deregulated microRNAome contributes to the cellular response to aneuploidy
Abstract Background Aneuploidy, or abnormal chromosome numbers, severely alters cell physiology and is widespread in cancers and other pathologies. Using model cell lines engineered to carry one or more extra chromosomes, it has been demonstrated that aneuploidy per se impairs proliferation, leads t...
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| Principais autores: | , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
BMC
2018-03-01
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| 叢編: | BMC Genomics |
| 主題: | |
| 在線閱讀: | http://link.springer.com/article/10.1186/s12864-018-4556-6 |
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