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Dual engagement of the nucleosomal acidic patches is essential for deposition of histone H2A.Z by SWR1C

The yeast SWR1C chromatin remodeling enzyme catalyzes the ATP-dependent exchange of nucleosomal histone H2A for the histone variant H2A.Z, a key variant involved in a multitude of nuclear functions. How the 14-subunit SWR1C engages the nucleosomal substrate remains largely unknown. Studies on the IS...

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Principais autores: Alexander S Baier, Nathan Gioacchini, Priit Eek, Erik M Leith, Song Tan, Craig L Peterson
Format: Artigo
Sprog:Inglês
Udgivet: eLife Sciences Publications Ltd 2024-05-01
Serier:eLife
Fag:
chromatin
H2A.Z
SWR1C
transcription
nucleosome
yeast
Online adgang:https://elifesciences.org/articles/94869
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