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Magnetic resonance imaging and ultrasound elastography in the context of preclinical pharmacological research: significance for the 3R principles

The 3Rs principles—reduction, refinement, replacement—are at the core of preclinical research within drug discovery, which still relies to a great extent on the availability of models of disease in animals. Minimizing their distress, reducing their number as well as searching for means to replace th...

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Principais autores: Michael Obrecht, Stefan Zurbruegg, Nathalie Accart, Christian Lambert, Arno Doelemeyer, Birgit Ledermann, Nicolau Beckmann
פורמט: Artigo
שפה:Inglês
יצא לאור: Frontiers Media S.A. 2023-06-01
סדרה:Frontiers in Pharmacology
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גישה מקוונת:https://www.frontiersin.org/articles/10.3389/fphar.2023.1177421/full
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