Pathological frataxin deficiency in mice causes tissue-specific alterations in iron homeostasis

Summary: Friedreich ataxia is caused by partial frataxin deficiency due to genetic mutations. It is well established that frataxin knockout affects iron homeostasis, but the alterations caused by pathological (partial) frataxin deficiency are poorly understood. In this study, we have analyzed iron h...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Maria Pazos-Gil, Marta Medina-Carbonero, Arabela Sanz-Alcázar, Marta Portillo-Carrasquer, Luiza Oliveira-Jorge, Gonzalo Hernández, Mayka Sánchez, Fabien Delaspre, Elisa Cabiscol, Joaquim Ros, Jordi Tamarit
Format:	Artigo
Jezik:	Inglês
Izdano:	Elsevier 2026-02-01
Serija:	iScience
Teme:	health sciences
Online dostop:	http://www.sciencedirect.com/science/article/pii/S258900422502886X
Oznake:	Označite Brez oznak, prvi označite!