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Cross-species analysis of genetic architecture and polygenic risk scores for non-contact ACL rupture in dogs and humans

Abstract Non-contact anterior cruciate ligament (ACL) rupture is a common serious orthopaedic disease in humans and dogs. Familial risk has been recognized in both species but interactions between genetic effects and environmental risk are not understood. We investigated ACL rupture heritability, ge...

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Бібліографічні деталі
Автори: Mehdi Momen, Hannah K. Kearney, Margaret M. Patterson, Susannah J. Sample, Zijie Zhao, Qiongshi Lu, Guilherme J. M. Rosa, Peter Muir
Формат: Artigo
Мова:Inglês
Опубліковано: Nature Portfolio 2025-01-01
Серія:Communications Biology
Онлайн доступ:https://doi.org/10.1038/s42003-024-07395-9
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