BACE1 inhibitors: A promising therapeutic approach for the management of Alzheimer’s disease

Alzheimer’s disease is a neurological disorder marked by the accumulation of amyloid beta (Aβ) aggregates, resulting from mutations in the amyloid precursor protein. The enzyme β-secretase, also known as β-site amyloid precursor protein cleaving enzyme 1 (BACE1), plays a crucial role in generating A...

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Bibliografski detalji

Glavni autori:	Richa Arya, Smita Jain, Sarvesh Paliwal, Kirtika Madan, Swapnil Sharma, Achal Mishra, Prashant Tiwari, Sunil Kumar Kadiri
Format:	Artigo
Jezik:	Inglês
Izdano:	Wolters Kluwer Medknow Publications 2024-09-01
Serija:	Asian Pacific Journal of Tropical Biomedicine
Teme:	bace1 inhibitors amyloid precursor protein β-secretase structure-based drug design 3d-qsar β-amyloid precursor protein
Online pristup:	https://journals.lww.com/10.4103/apjtb.apjtb_192_24
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