The Hunt for Degrons of the 26S Proteasome

Since the discovery of ubiquitin conjugation as a cellular mechanism that triggers proteasomal degradation, the mode of substrate recognition by the ubiquitin-ligation system has been the holy grail of research in the field. This entails the discovery of recognition determinants within protein subst...

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書目詳細資料

Principais autores:	Hadar Ella, Yuval Reiss, Tommer Ravid
格式:	Artigo
語言:	Inglês
出版:	MDPI AG 2019-06-01
叢編:	Biomolecules
主題:	ubiquitin-proteasome system degrons E3-ubiquitin ligases protein quality control high throughput screens next generation sequencing
在線閱讀:	https://www.mdpi.com/2218-273X/9/6/230
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