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The ameliorating effects of Guizhi Fuling Wan combined with rosiglitazone in a rat ovarian model of polycystic ovary syndrome by the PI3K/AKT/NF-κB and Nrf2/HO-1 pathways

Objective GuizhiFulingWan (GFW) has been reported to be effective against polycystic ovary syndrome (PCOS) by possessing oxidative stress and inflammation which related to PI3K/AKT/NF-κB, Nrf2/HO-1 pathway. This study aims to probe the effects and mechanisms of GFW combined with rosiglitazone on PCO...

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Main Authors: Yongju Ye, Weimei Zhou, Yuefang Ren, Jiali Lu, Aixue Chen, Ruiying Jin, Feilan Xuan
Format: Artigo
Language:Inglês
Published: Taylor & Francis Group 2023-12-01
Series:Gynecological Endocrinology
Subjects:
Polycystic ovary syndrome
guizhi fuling wan
rosiglitazone
PI3K/AKT/NF-κB pathway
Nrf2/HO-1 pathway
Online Access:https://www.tandfonline.com/doi/10.1080/09513590.2023.2254848
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