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Developing Novel G-Quadruplex Ligands: from Interaction with Nucleic Acids to Interfering with Nucleic Acid–Protein Interaction

G-quadruplex is a special secondary structure of nucleic acids in guanine-rich sequences of genome. G-quadruplexes have been proved to be involved in the regulation of replication, DNA damage repair, and transcription and translation of oncogenes or other cancer-related genes. Therefore, targeting G...

Ausführliche Beschreibung

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Bibliografische Detailangaben
Hauptverfasser: Zhi-Yin Sun, Xiao-Na Wang, Sui-Qi Cheng, Xiao-Xuan Su, Tian-Miao Ou
Format: Artigo
Sprache:Inglês
Veröffentlicht: MDPI AG 2019-01-01
Schriftenreihe:Molecules
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Online-Zugang:https://www.mdpi.com/1420-3049/24/3/396
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