Activation of the constitutive androstane receptor decreases HDL in wild-type and human apoA-I transgenic mice

The nuclear hormone receptor constitutive androstane receptor (CAR, NR1I3) regulates detoxification of xenobiotics and endogenous molecules, and has been shown to be involved in the metabolism of hepatic bile acids and cholesterol. The goal of this study was to address potential effects of CAR on th...

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Библиографические подробности

Главные авторы:	David Masson, Mohamed Qatanani, Anne Laure Sberna, Rui Xiao, Jean Paul Pais de Barros, Jacques Grober, Valerie Deckert, Anne Athias, Philippe Gambert, Laurent Lagrost, David D. Moore, Mahfoud Assem
Формат:	Artigo
Язык:	Inglês
Опубликовано:	Elsevier 2008-08-01
Серии:	Journal of Lipid Research
Предметы:	apolipoprotein A-I bile acids cholesterol 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene
Online-ссылка:	http://www.sciencedirect.com/science/article/pii/S0022227520346861
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