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CD44: A Multifunctional Mediator of Cancer Progression

CD44, a non-kinase cell surface transmembrane glycoprotein, has been widely implicated as a cancer stem cell (CSC) marker in several cancers. Cells overexpressing CD44 possess several CSC traits, such as self-renewal and epithelial-mesenchymal transition (EMT) capability, as well as a resistance to...

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Principais autores: Malak Hassn Mesrati, Saiful Effendi Syafruddin, M. Aiman Mohtar, Amir Syahir
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI AG 2021-12-01
coleção:Biomolecules
Assuntos:
CD44
regulation
tumourigenesis
signalling pathways
prognosis
therapeutic targeting
Acesso em linha:https://www.mdpi.com/2218-273X/11/12/1850
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