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RAD6 Positively Affects Tumorigenesis of Esophageal Squamous Cell Carcinoma by Regulating Histone Ubiquitination of CCNB1

Abstract Objective Esophageal carcinoma (ESCA) is deadly cancer worldwide with unknown etiology. This study aimed to investigate the impact and mechanism of RAD6 on the development of Esophageal squamous cell carcinoma (ESCC). Expressions of RAD6A and RAD6B in ESCA were investigated from TCGA datase...

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Principais autores: Yu Deng, Yujiang Li, Tiantong Wu, Xuyuan Chen, Xiang Li, Kaican Cai, Xu Wu
Format: Artigo
Sprog:Inglês
Udgivet: BMC 2022-03-01
Serier:Biological Procedures Online
Fag:
Esophageal squamous cell carcinoma
RAD6A
RAD6B
CCNB1
Ubiquitin
Online adgang:https://doi.org/10.1186/s12575-022-00165-z
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