RIG-I detects triphosphorylated RNA of Listeria monocytogenes during infection in non-immune cells.

The innate immune system senses pathogens by pattern recognition receptors in different cell compartments. In the endosome, bacteria are generally recognized by TLRs; facultative intracellular bacteria such as Listeria, however, can escape the endosome. Once in the cytosol, they become accessible to...

Ausführliche Beschreibung

Bibliografische Detailangaben

Hauptverfasser:	Cristina Amparo Hagmann, Anna Maria Herzner, Zeinab Abdullah, Thomas Zillinger, Christopher Jakobs, Christine Schuberth, Christoph Coch, Paul G Higgins, Hilmar Wisplinghoff, Winfried Barchet, Veit Hornung, Gunther Hartmann, Martin Schlee
Format:	Artigo
Sprache:	Inglês
Veröffentlicht:	Public Library of Science (PLoS) 2013-01-01
Schriftenreihe:	PLoS ONE
Online-Zugang:	https://journals.plos.org/plosone/article/file?id=10.1371/journal.pone.0062872&type=printable
Tags:	Tag hinzufügen Keine Tags, Fügen Sie das erste Tag hinzu!