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The COX- inhibitor indomethacin reduces Th1 effector and T regulatory cells in vitro in Mycobacterium tuberculosis infection

Abstract Background Tuberculosis (TB) causes a major burden on global health with long and cumbersome TB treatment regimens. Host-directed immune modulating therapies have been suggested as adjunctive treatment to TB antibiotics. Upregulated cyclooxygenase-2 (COX-2)-prostaglandin E2 (PGE2) signaling...

Whakaahuatanga katoa

I tiakina i:
Ngā taipitopito rārangi puna kōrero
Ngā kaituhi matua: Kristian Tonby, Ida Wergeland, Nora V. Lieske, Dag Kvale, Kjetil Tasken, Anne M. Dyrhol-Riise
Hōputu: Artigo
Reo:Inglês
I whakaputaina: BMC 2016-10-01
Rangatū:BMC Infectious Diseases
Ngā marau:
Urunga tuihono:http://link.springer.com/article/10.1186/s12879-016-1938-8
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