MCM8 interacts with DDX5 to promote R-loop resolution

Abstract MCM8 has emerged as a core gene in reproductive aging and is crucial for meiotic homologous recombination repair. It also safeguards genome stability by coordinating the replication stress response during mitosis, but its function in mitotic germ cells remains elusive. Here we found that di...

Popoln opis

Bibliografske podrobnosti

Principais autores:	Canxin Wen, Lili Cao, Shuhan Wang, Weiwei Xu, Yongze Yu, Simin Zhao, Fan Yang, Zi-Jiang Chen, Shidou Zhao, Yajuan Yang, Yingying Qin
Format:	Artigo
Jezik:	Inglês
Izdano:	Springer Nature 2024-06-01
Serija:	The EMBO Journal
Teme:	Primordial Germ Cells MCM8 R-loop Genome Stability Fertility
Online dostop:	https://doi.org/10.1038/s44318-024-00134-0
Oznake:	Označite Brez oznak, prvi označite!