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Development of In Vitro Evaluation System for Assessing Drug Dissolution Considering Physiological Environment in Nasal Cavity

Estimating the dissolution behavior of a solid in the nasal mucus is challenging for solid dosage forms designed for the nasal application as the solid dissolves into nasal mucus and permeates through the mucosa. In the current study, the dissolution behavior of powders in the artificial nasal fluid...

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Hlavní autoři: Daisuke Inoue, Ayari Yamashita, Hideto To
Médium: Artigo
Jazyk:Inglês
Vydáno: MDPI AG 2022-10-01
Edice:Pharmaceutics
Témata:
nasal formulation
powder formulation
nasal absorption
nasal mucus
Calu-3 cell line
mucosal permeation
On-line přístup:https://www.mdpi.com/1999-4923/14/11/2350
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