Genome-wide analysis of PDZ domain binding reveals inherent functional overlap within the PDZ interaction network.

Binding selectivity and cross-reactivity within one of the largest and most abundant interaction domain families, the PDZ family, has long been enigmatic. The complete human PDZ domain complement (the PDZome) consists of 267 domains and we applied here a Bayesian selectivity model to predict hundred...

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Bibliografiske detaljer

Principais autores:	Aartjan J W te Velthuis, Philippe A Sakalis, Donald A Fowler, Christoph P Bagowski
Format:	Artigo
Sprog:	Inglês
Udgivet:	Public Library of Science (PLoS) 2011-01-01
Serier:	PLoS ONE
Online adgang:	https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/21283644/?tool=EBI
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