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Protective Effects of ACE/NEP Dual Inhibitor Omapatrilat for Indomethacin-induced Gastric Ulcer

Aim: The renin-angiotensin-aldosterone system (RAAS) plays important roles in oxidative stress and various gastroenterological mechanisms. Omapatrilat, an RAAS-acting agent, inhibits both neprilysin neutral endopeptidase (NEP) and angiotensin converting enzyme (ACE) and may therefore affect protecti...

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Main Authors: Kadir Giray ERKAYMAN, Rüstem Anıl UĞAN, Zeynep Berna AKSAKALLI MAĞDEN, Eda YILMAZ, Ayşe BOZKURT, Elif ÇADIRCI
Format: Artigo
Language:Inglês
Published: Tekirdağ Namık Kemal University 2023-12-01
Series:Namık Kemal Tıp Dergisi
Subjects:
gastric ulcer
indomethacin
neprilysin
oxidative stress
omapatrilat
Online Access: http://namikkemalmedj.com/archives/archive-detail/article-preview/protective-effects-of-ace-nep-dual-nhibitor-omapat/63799
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