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A Markov chain Monte Carlo model of mechanical-feedback-driven progressive apical constrictions captures the fluctuating collective cell dynamics in the Drosophila embryo

Communication via mechanical stress feedback is believed to play an important role in the intercellular coordination of collective cellular movements. One such movement is ventral furrow formation (VFF) in the Drosophila melanogaster embryo. We previously introduced an active granular fluid (AGF) mo...

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Principais autores: Guo–Jie J. Gao, Michael C. Holcomb, Jeffrey H. Thomas, Jerzy Blawzdziewicz
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2022-10-01
Serier:Frontiers in Physics
Fag:
Drosophila
embryo
morphogenesis
ventral furrow formation
cellular constrictions
mechanical feedback
Online adgang:https://www.frontiersin.org/articles/10.3389/fphy.2022.971112/full
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