Fast-exchanging spirocyclic rhodamine probes for aptamer-based super-resolution RNA imaging
Abstract Live-cell RNA imaging with high spatial and temporal resolution remains a major challenge. Here we report the development of RhoBAST:SpyRho, a fluorescent light-up aptamer (FLAP) system ideally suited for visualizing RNAs in live or fixed cells with various advanced fluorescence microscopy...
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| Principais autores: | , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Portfolio
2023-06-01
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| Serier: | Nature Communications |
| Online adgang: | https://doi.org/10.1038/s41467-023-39611-1 |
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