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Rational Drug Design of Axl Tyrosine Kinase Type I Inhibitors as Promising Candidates Against Cancer

The high level of Axl tyrosine kinase expression in various cancer cell lines makes it an attractive target for the development of anti-cancer drugs. In this study, we carried out several sets of in silico screening for the ATP-competitive Axl kinase inhibitors based on different molecular docking p...

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Bibliografiske detaljer
Principais autores: Edita Sarukhanyan, Sergey Shityakov, Thomas Dandekar
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2020-02-01
Serier:Frontiers in Chemistry
Fag:
Online adgang:https://www.frontiersin.org/article/10.3389/fchem.2019.00920/full
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