Abiraterone and MDV3100 inhibits the proliferation and promotes the apoptosis of prostate cancer cells through mitophagy

Abstract Background Abiraterone and MDV3100 are two effective anticancer agents for prostate cancer, however, the mechanism of their downstream action remains undefined. Methods A dual fluorescent biosensor plasmid was transfected in LNCaP cells to measure mitophagy. The DNA of LNCaP cells was extra...

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Bibliografiske detaljer

Principais autores:	Jingli Han, Junhua Zhang, Wei Zhang, Dalei Zhang, Ying Li, Jinsong Zhang, Yaqun Zhang, Tongxiang Diao, Luwei Cui, Wenqing Li, Fei Xiao, Ming Liu, Lihui Zou
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2019-12-01
Serier:	Cancer Cell International
Fag:	Prostate cancer Mitophagy Abiraterone MDV3100
Online adgang:	https://doi.org/10.1186/s12935-019-1021-9
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