Astaxanthin stimulates mitochondrial biogenesis in insulin resistant muscle via activation of AMPK pathway

Abstract Background Skeletal muscle is mainly responsible for insulin‐stimulated glucose disposal. Dysfunction in skeletal muscle metabolism especially during obesity contributes to the insulin resistance. Astaxanthin (AX), a natural antioxidant, has been shown to ameliorate hepatic insulin resistan...

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主要な著者:	Yasuhiro Nishida, Allah Nawaz, Tomonobu Kado, Akiko Takikawa, Yoshiko Igarashi, Yasuhiro Onogi, Tsutomu Wada, Toshiyasu Sasaoka, Seiji Yamamoto, Masakiyo Sasahara, Johji Imura, Kumpei Tokuyama, Isao Usui, Takashi Nakagawa, Shiho Fujisaka, Yagi Kunimasa, Kazuyuki Tobe
フォーマット:	Artigo
言語:	Inglês
出版事項:	Wiley 2020-02-01
シリーズ:	Journal of Cachexia, Sarcopenia and Muscle
主題:	Astaxanthin Mitchondrial biogenesis Exercise‐endurance Skeletal muscle remodeling AMPK activation insulin resistance
オンライン･アクセス:	https://doi.org/10.1002/jcsm.12530
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