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RavA‐ViaA antibiotic response is linked to Cpx and Zra2 envelope stress systems in Vibrio cholerae

ABSTRACT RavA-ViaA were reported to play a role in aminoglycoside (AG) sensitivity, but the mechanisms remain elusive. Here, we performed competition and survival experiments to confirm that deletion of ravA-viaA increases tolerance of the Gram-negative pathogen Vibrio cholerae to low and high AG co...

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Principais autores: Evelyne Krin, André Carvalho, Manon Lang, Anamaria Babosan, Didier Mazel, Zeynep Baharoglu
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2023-12-01
Serier:Microbiology Spectrum
Fag:
antibiotic resistance
antibiotic tolerance
ravA viaA
bacterial membrane
Vibrio cholerae
sub-MIC antibiotics
Online adgang:https://journals.asm.org/doi/10.1128/spectrum.01730-23
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