Endothelial GPR68 Is Essential for Arteriogenesis and Represents a Therapeutic Target in a Model of Peripheral Artery Disease

ABSTRACT Peripheral artery disease (PAD) is characterized by arterial narrowing that reduces limb perfusion, causing significant morbidity. The body can compensate via shear stress‐driven collateral artery growth (arteriogenesis). However, the primary receptors of mechanical forces on the endothelia...

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Hlavní autoři:	Yiyan Song, Senyi Peng, Zhilei Huang, Miao Yu, Mingyue Wu, Yuexin Zhu, Zeyi Zhou, Yongshan Liu, Yalin Zhang, Yu Huang, Zhongxing Wang, Fu‐Li Xiang, Jie Xu
Médium:	Artigo
Jazyk:	Inglês
Vydáno:	Wiley 2026-06-01
Edice:	Advanced Science
Témata:	Arteriogenesis GPR68 Hindlimb Ischemia (HLI) Peripheral Artery Diseases
On-line přístup:	https://doi.org/10.1002/advs.202520244
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