A new rat model of creatine transporter deficiency reveals behavioral disorder and altered brain metabolism

Abstract Creatine is an organic compound used as fast phosphate energy buffer to recycle ATP, important in tissues with high energy demand such as muscle or brain. Creatine is taken from the diet or endogenously synthetized by the enzymes AGAT and GAMT, and specifically taken up by the transporter S...

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Principais autores:	Lara Duran-Trio, Gabriella Fernandes-Pires, Dunja Simicic, Jocelyn Grosse, Clothilde Roux-Petronelli, Stephen J. Bruce, Pierre-Alain Binz, Carmen Sandi, Cristina Cudalbu, Olivier Braissant
פורמט:	Artigo
שפה:	Inglês
יצא לאור:	Nature Portfolio 2021-01-01
סדרה:	Scientific Reports
גישה מקוונת:	https://doi.org/10.1038/s41598-020-80824-x
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