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Mechanisms of ubiquitin-independent proteasomal degradation and their roles in age-related neurodegenerative disease

Neurodegenerative diseases are characterized by the progressive breakdown of neuronal structure and function and the pathological accumulation of misfolded protein aggregates and toxic protein oligomers. A major contributor to the deterioration of neuronal physiology is the disruption of protein cat...

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Збережено в:
Бібліографічні деталі
Автори: Taylor R. Church, Seth S. Margolis
Формат: Artigo
Мова:Inglês
Опубліковано: Frontiers Media S.A. 2025-02-01
Серія:Frontiers in Cell and Developmental Biology
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Онлайн доступ:https://www.frontiersin.org/articles/10.3389/fcell.2024.1531797/full
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