Inhibition of Hepatic Bile Acid Uptake by Myrcludex B Promotes Glucagon-Like Peptide-1 Release and Reduces ObesitySummary

Background & Aims: Bile acids are important metabolic signaling molecules. Bile acid receptor activation promotes body weight loss and improves glycemic control. The incretin hormone GLP-1 and thyroid hormone activation of T4 to T3 have been suggested as important contributors. Here, we identify...

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Autori principali:	Joanne M. Donkers, Reinout L.P. Roscam Abbing, Michel van Weeghel, Johannes H.M. Levels, Anita Boelen, Alfred H. Schinkel, Ronald P.J. Oude Elferink, Stan F.J. van de Graaf
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Elsevier 2020-01-01
Serie:	Cellular and Molecular Gastroenterology and Hepatology
Soggetti:	NTCP OATP Myrcludex B Obesity
Accesso online:	http://www.sciencedirect.com/science/article/pii/S2352345X20300539
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