SASP Modulation for Cellular Rejuvenation and Tissue Homeostasis: Therapeutic Strategies and Molecular Insights

Cellular senescence regulates aging, tissue maintenance, and disease progression through the Senescence-Associated Secretory Phenotype (SASP), a secretory profile of cytokines, chemokines, growth factors, and matrix-remodeling enzymes. While transient SASP aids wound healing, its chronic activation...

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Detalhes bibliográficos

Principais autores:	Saud Alqahtani, Taha Alqahtani, Krishnaraju Venkatesan, Durgaramani Sivadasan, Rehab Ahmed, Nizar Sirag, Hassabelrasoul Elfadil, Hanem Abdullah Mohamed, Haseena T.A., Rasha Elsayed Ahmed, Pooja Muralidharan, Premalatha Paulsamy
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2025-04-01
coleção:	Cells
Assuntos:	cellular senescence senescence-associated secretory phenotype (SASP) cellular rejuvenation aging and tissue homeostasis SASP modulation strategies
Acesso em linha:	https://www.mdpi.com/2073-4409/14/8/608
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