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Properties and molecular determinants of the natural flavone acacetin for blocking hKv4.3 channels.

The natural flavone acacetin has been demonstrated to inhibit transient outward potassium current (Ito) in human atrial myocytes. However, the molecular determinants of acacetin for blocking Ito are unknown. The present study was designed to investigate the properties and molecular determinants of t...

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Bibliografske podrobnosti
Principais autores: Hui-Jun Wu, Hai-Ying Sun, Wei Wu, Yan-Hui Zhang, Guo-Wei Qin, Gui-Rong Li
Format: Artigo
Jezik:Inglês
Izdano: Public Library of Science (PLoS) 2013-01-01
Serija:PLoS ONE
Online dostop:http://europepmc.org/articles/PMC3603988?pdf=render
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