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Two distinct modes of Vgll4-mediated Tead regulation control organ size in zebrafish

Abstract Control of organ size during development and homeostasis relies on balanced regulation of Hippo pathway transcriptional output, yet how TEAD activity is precisely regulated in vivo remains unclear. Using the zebrafish posterior lateral line (pLL) we show that Yap1 is required early in pLL p...

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Ngā kaituhi matua: Alicia Lardennois, Veronika Duda, Chaitanya Dingare, Petra A. Klemmt, Constanze Heinzen, Lucas Desruelles, Melanie Heyde, David Simon Kleinhans, Thorsten Falk, Carsten Schelmbauer, Olivia Mozolewska, Sofia Papadopoulou, Jason J. K. Lai, Didier Y. R. Stainier, Virginie Lecaudey
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Nature Portfolio 2026-04-01
Rangatū:Communications Biology
Urunga tuihono:https://doi.org/10.1038/s42003-026-10098-y
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