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Chromosome Preference During Homologous Recombination Repair of DNA Double-Strand Breaks in Drosophila melanogaster

DNA double-strand breaks (DSBs) are especially toxic DNA lesions that, if left unrepaired, can lead to wide-ranging genomic instability. Of the pathways available to repair DSBs, the most accurate is homologous recombination (HR), where a homologous sequence is used as a donor template to restore ge...

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Principais autores: Joel Fernandez, Hanan Bloomer, Natalia Kellam, Jeannine R. LaRocque
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2019-11-01
Serier:G3: Genes, Genomes, Genetics
Fag:
dsb repair
homologous recombination
drosophila melanogaster
interhomolog recombination
intrachromosomal recombination
Online adgang:http://g3journal.org/lookup/doi/10.1534/g3.119.400607
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