Structure of Myosin VI/Tom1 complex reveals a cargo recognition mode of Myosin VI for tethering

Myosin VI can facilitate the maturation of autophagosomes in autophagy through interactions with Tom1 and autophagy receptors. Here authors report the structure of the cargobinding domain of Myosin VI in complex with Tom1, which provides insights into Myosin IV’s cargo recognition modes.

Détails bibliographiques

Auteurs principaux:	Shichen Hu, Yujiao Guo, Yingli Wang, Ying Li, Tao Fu, Zixuan Zhou, Yaru Wang, Jianping Liu, Lifeng Pan
Format:	Artigo
Langue:	Inglês
Publié:	Nature Portfolio 2019-08-01
Collection:	Nature Communications
Accès en ligne:	https://doi.org/10.1038/s41467-019-11481-6
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