KCC2 activation during postnatal development alleviates long-term deficits in CDKL5-deficient mice
Abstract Cyclin-dependent kinase-like 5 (CDKL5) deficiency disorder (CDD) is a severe developmental and epileptic encephalopathy characterized by early onset drug-resistant seizures and later cognitive and social impairments. Existing therapies primarily involve antiseizure medications, which have s...
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| Автори: | , , , , , , , , , |
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| Формат: | Artigo |
| Мова: | Inglês |
| Опубліковано: |
Nature Publishing Group
2026-02-01
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| Серія: | Experimental and Molecular Medicine |
| Онлайн доступ: | https://doi.org/10.1038/s12276-026-01670-x |
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