Insights on the Multifaceted Roles of Wild-Type and Mutated Superoxide Dismutase 1 in Amyotrophic Lateral Sclerosis Pathogenesis

Amyotrophic Lateral Sclerosis (ALS) is a progressive motor neurodegenerative disease. Cell damage in ALS is the result of many different, largely unknown, pathogenetic mechanisms. Astrocytes and microglial cells play a critical role also for their ability to enhance a deranged inflammatory response....

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Detalhes bibliográficos

Principais autores:	Valentina Rubino, Giuliana La Rosa, Luca Pipicelli, Flavia Carriero, Simona Damiano, Mariarosaria Santillo, Giuseppe Terrazzano, Giuseppina Ruggiero, Paolo Mondola
Formato:	Artigo
Idioma:	Inglês
Publicado em:	MDPI AG 2023-09-01
coleção:	Antioxidants
Assuntos:	Amyotrophic Lateral Sclerosis (ALS) Superoxide Dismutase 1 (SOD1) intracellular signaling immune response regulation excitotoxicity neurodegeneration
Acesso em linha:	https://www.mdpi.com/2076-3921/12/9/1747
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