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Acquisition of N-Glycosylation Sites in Immunoglobulin Heavy Chain Genes During Local Expansion in Parotid Salivary Glands of Primary Sjögren Patients

Previous studies revealed high incidence of acquired N-glycosylation sites acquired N-glycosylation sites in RNA transcripts encoding immunoglobulin heavy variable region (IGHV) 3 genes from parotid glands of primary Sjögren’s syndrome (pSS) patients. In this study, next generation sequencing was us...

Whakaahuatanga katoa

I tiakina i:
Ngā kaituhi matua: Annie Visser, Marieke E. Doorenspleet, Niek de Vries, Fred K. L. Spijkervet, Arjan Vissink, Richard J. Bende, Hendrika Bootsma, Frans G. M. Kroese, Nicolaas A. Bos
Hōputu: Artigo
Reo:Inglês
I whakaputaina: Frontiers Media S.A. 2018-03-01
Rangatū:Frontiers in Immunology
Ngā marau:
Sjögren syndrome
B-cell
N-glycosylation
heavy chain
parotid Gland
next generation sequencing
Urunga tuihono:http://journal.frontiersin.org/article/10.3389/fimmu.2018.00491/full
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