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Evaluating the impact of relative dose intensity on efficacy of trastuzumab deruxtecan for metastatic breast cancer in the real-world clinical setting

Introduction: Trastuzumab deruxtecan (T-DXd) has revolutionised treatment for metastatic breast cancer (MBC). While effective, its high cost and toxicities, such as fatigue and nausea, pose challenges. Method: Medical records from the Joint Breast Cancer Registry in Singapore were used to study MBC...

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Auteurs principaux: Han Yi Lee, Vivianne Shih, Jack Junjie Chan, Shun Zi Liong, Ryan Shea Ying Cong Tan, Jun Ma, Bernard Ji Guang Chua, Joshua Zhi Chien Tan, Chuan Yaw Lee, Wei Ling Teo, Su-Ming Tan, Phyu Nitar, Yoon Sim Yap, Mabel Wong, Rebecca Dent, Fuh Yong Wong, Tira J Tan
Format: Artigo
Langue:Inglês
Publié: Academy of Medicine Singapore 2025-08-01
Collection:Annals, Academy of Medicine, Singapore
Accès en ligne:https://annals.edu.sg/evaluating-the-impact-of-relative-dose-intensity-on-efficacy-of-trastuzumab-deruxtecan-for-metastatic-breast-cancer-in-the-real-world-clinical-setting/
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