IL-2RG as a possible immunotherapeutic target in CRC predicting poor prognosis and regulated by miR-7-5p and miR-26b-5p

Abstract Despite advances in treatment strategies, colorectal cancer (CRC) continues to cause significant morbidity and mortality, with mounting evidence a close link between immune system dysfunctions issued. Interleukin-2 receptor gamma (IL-2RG) plays a pivotal role as a common subunit receptor in...

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Bibliografiske detaljer

Principais autores:	Ehsan Gharib, Leili Rejali, Moein Piroozkhah, Elham Zonoobi, Parinaz Nasri Nasrabadi, Zahra Arabsorkhi, Kaveh Baghdar, Elahe Shams, Amir Sadeghi, Peter J. K. Kuppen, Zahra Salehi, Ehsan Nazemalhosseini-Mojarad
Format:	Artigo
Sprog:	Inglês
Udgivet:	BMC 2024-05-01
Serier:	Journal of Translational Medicine
Fag:	Colorectal cancer Interleukin-2 receptor gamma Tumor-infiltrating lymphocytes Hsa-miR-7-5p Hsa-miR-26b-5p Biomarker
Online adgang:	https://doi.org/10.1186/s12967-024-05251-2
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